There exists a definite and logical chain between pain, brain activity and disorders. The Journal of Neuroscience helped to understand this connection. According to a new study the brain's state of equilibrium is disrupted when a man suffers from chronic pains.
Chronic pains keep some areas of brain - mainly the frontal cortex - active all the time. This causes inability to deactivate when it required and necessary. This in its turn keeps neurons firing. If neurons fire too much they may change their connections with other neurons and or even die because they can't sustain high activity for so long.
Now fancy what you can lose.
The frontal cortex or lobes have been found to play a part in impulse control, judgment, language production, working memory, motor function, sexual behavior, socialization, problem solving initiation, facial movement, planning abilities, coordinating, and motivation. The frontal lobes assist in planning, coordinating, controlling, and executing behavior. People who have damaged frontal lobes may experience problems with these aspects of cognitive function, being at times impulsive; impaired in their ability to plan and execute complex sequences of actions; perhaps persisting with one course of action or pattern of behavior when a change would be appropriate.